• Introduction and Approval: Sculptra, a polymerized lactic acid product, was introduced to the aesthetic dermatology field in 2004, initially approved by the FDA for treating HIV-associated lipoatrophy. Its acceptance among cosmetic dermatologists and plastic surgeons has grown, supported by clinical trials for aesthetic indications (Beer & Rendon, 2006).
• Efficacy for Facial Rejuvenation: Systematic reviews and clinical studies indicate Sculptra is an effective, safe, and long-lasting agent for collagen volumization and biostimulation. It is considered beneficial for facial rejuvenation, with effects lasting up to 25 months. Optimal results require knowledge of facial anatomy, correct treatment procedures, appropriate injection techniques, and proper patient aftercare (Menezes et al., 2022).
• Novel Technique and Mechanism: Sculptra’s unique mechanism of action requires a shift in the approach to treating specific lines to returning volume to facial areas. It has been successfully used for correcting nasolabial folds, mid and lower facial volume loss, jawline laxity, and other signs of facial aging (Vleggaar & Bauer, 2004).
• Soft Tissue Augmentation: Sculptra provides a minimally invasive option for effective and prolonged facial enhancement correction with a low frequency of side effects. It is distinguished by its ability to stimulate inflammatory tissue response and subsequent collagen deposition, contributing to soft tissue volume restoration (Schierle & Casas, 2011).
• European Expert Recommendations: To achieve optimal results with Sculptra, detailed knowledge of the correct dilution, injection technique, and patient aftercare is crucial. It is highlighted as an effective collagen stimulator that treats the whole face, easy to combine with other treatments, providing long-lasting effects with high patient satisfaction (Alessio et al., 2014).

In summary, Sculptra is an effective, safe, and long-lasting option for facial rejuvenation, offering volume restoration and contour enhancement. Proper technique and patient management are essential for achieving the best outcomes.